Scientists in UT Houston laboratory of Sudhir Paul, Ph.D., may have uncovered a chink the armor of the deadly HIV virus. Pictured from left to right are: Paul, Yasuhiro Nishiyama, Ph.D., and Stephanie Planque. (Credit: Image courtesy of University of Texas Health Science Center at Houston)
The weak spot is hidden in the HIV envelope protein gp120. This protein is essential for HIV attachment to host cells, which initiate infection and eventually lead to Acquired Immunodeficiency Syndrome or AIDS...The Achilles heel, a tiny stretch of amino acids numbered 421-433 on gp120, is now under study as a target for therapeutic intervention.
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